United States securities and exchange commission logo October 29, 2021 Raluca Dinu Chief Executive Officer GigCapital4, Inc. 1731 Embarcadero Road, Suite 200 Palo Alto, California 94303 Re: GigCapital4, Inc. Revised Preliminary Proxy Statement on Schedule 14A Filed October 27, 2021 File No. 001-40031 Dear Dr. Dinu: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Technology cc: Jeffrey C. Selman